What is Meropenem Avibactam Injection?

Ulmero A 1.5 is a brand name of Meropenem avibactam Injection is a combination antibiotic useful in treating severe bacterial infection especially those caused due to drug-resistant bacteria and it is completely safe to buy from www.plenumbiotech.com at affordable price in India.

Uses of Meropenem Avibactam Injection

Meropenem: A carbapenem antibiotic works by inhibiting bacterial cell wall synthesis leading to bacterial death.

Avibactam: A beta-lactamase inhibitor prevents bacterial enzymes from breaking down meropenem making the antibiotic more effective against resistant bacteria. 

Complicated urinary tract Infection (UTIs): Useful in treating severe UTIs including pyelonephritis (kidney infection)

• Effective against bacteria resistant to other antibiotics such as extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae

Complicated Intra-Abdominal infections (cIAIs)

• Often useful in combination with metronidazole to treat infections in the stomach, intestines or abdominal organs.
• Effective against E.coli, Klebsiella pneumoniae, and Pseudomonas, aeruginosa that are common causes of abdominal infection

Multidrug-Resistant (MDR) Gram-Negative Bacterial Infections

• Effective against carbapenem-resistant Enterobacteriaceae (CRE) and Klebsiella pneumoniae carbapenems (KPC)-producing bacteria.
• Used when bacteria have developed resistance to other carbapenems like imipenem or doripenem.

Precautions and Side effects of Meropenem Avibactam Injection

• Medical Supervision – Should only be given in hospitals by healthcare professionals
• Allergy Risk – Avoid if allergic to meropenem, avibactam, or beta-lactam antibiotics (penicillins, cephalosporins). Watch for rash, swelling, or breathing issues
• Kidney Issue– Dose adjustments are needed for patients with kidney disease. Regular monitoring is required
• Seizure Risk – May cause seizures or confusion, especially in patients with a history of epilepsy
• Pregnancy & Breastfeeding – Use only if clearly needed; consult a healthcare provider

Side Effects:

• Diarrhea
• Nausea
• Vomiting
• Rash
• Infusion site vesicles

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